KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRWD1
All Species:
13.33
Human Site:
T2290
Identified Species:
29.33
UniProt:
Q9NSI6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NSI6
NP_061836.2
2320
262920
T2290
V
Y
K
E
D
D
T
T
I
N
S
E
S
E
K
Chimpanzee
Pan troglodytes
XP_001170924
2320
262999
T2290
V
Y
K
E
D
D
T
T
I
N
S
E
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001108655
2320
262912
T2290
V
Y
K
E
D
D
T
T
I
N
S
E
S
E
K
Dog
Lupus familis
XP_544889
2401
270094
T2372
V
Y
K
E
D
D
T
T
R
N
S
D
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q921C3
2304
259007
P2278
V
Y
K
E
D
D
A
P
I
H
S
E
N
E
K
Rat
Rattus norvegicus
XP_001054667
1799
202807
L1774
S
T
E
D
P
L
N
L
G
T
S
R
S
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510724
2599
293992
G2329
I
S
E
E
N
D
A
G
F
R
Y
D
S
E
R
Chicken
Gallus gallus
XP_416730
2299
260504
N2272
R
T
K
I
R
T
R
N
R
G
R
R
T
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920441
2191
247687
D2163
V
V
S
D
D
D
S
D
V
S
F
E
K
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395863
1676
190205
P1651
S
P
E
P
E
N
V
P
R
I
S
I
S
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201169
1837
210307
D1812
N
L
Q
S
G
E
E
D
D
G
K
S
V
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
85.7
N.A.
78.7
44.7
N.A.
65.6
61.8
N.A.
44.7
N.A.
N.A.
34.9
N.A.
27.3
Protein Similarity:
100
99.7
98.7
89.7
N.A.
86.1
57.7
N.A.
74.3
73.4
N.A.
61.4
N.A.
N.A.
49.4
N.A.
42.3
P-Site Identity:
100
100
100
86.6
N.A.
73.3
13.3
N.A.
26.6
6.6
N.A.
26.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
33.3
N.A.
60
20
N.A.
60
N.A.
N.A.
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
55
64
0
19
10
0
0
19
0
0
0
% D
% Glu:
0
0
28
55
10
10
10
0
0
0
0
46
0
55
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
10
19
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
37
10
0
10
0
0
0
% I
% Lys:
0
0
55
0
0
0
0
0
0
0
10
0
10
0
46
% K
% Leu:
0
10
0
0
0
10
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
10
10
10
0
37
0
0
10
0
0
% N
% Pro:
0
10
0
10
10
0
0
19
0
0
0
0
0
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
0
10
0
28
10
10
19
0
0
46
% R
% Ser:
19
10
10
10
0
0
10
0
0
10
64
10
64
19
10
% S
% Thr:
0
19
0
0
0
10
37
37
0
10
0
0
10
0
0
% T
% Val:
55
10
0
0
0
0
10
0
10
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
46
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _